Ideal, expected and perceived descriptive norm drunkenness in UK nightlife environments: a cross-sectional study

Abstract Background Drunkenness is common in nightlife environments and studies suggest it can be considered both desirable and normal by nightlife users. We aimed to compare UK nightlife users’ ideal levels of drunkenness to their expected drunkenness on a night out and their perceptions of descriptive nightlife norms. Methods A cross-sectional survey with nightlife patrons (n = 408, aged 18–35) in three cities. Using a scale from 1 (completely sober) to 10 (very drunk), participants rated: personal drunkenness at survey; expected drunkenness on leaving nightlife; perceived descriptive drunkenness norm in the city’s nightlife; and ideal personal drunkenness. Analyses were limited to those who had or were intending to consume alcohol. Results Almost half of participants (46.8%) expected to get drunker than their reported ideal level on the night of survey, rising to four fifths of those with the highest levels of expected drunkenness. 77.9% rated typical nightlife drunkenness ≥8 but only 40.9% expected to reach this level themselves and only 23.1% reported their ideal drunkenness as ≥8. Higher expected drunkenness was associated with higher ideal drunkenness, higher perceived drunkenness norm and later expected home time. Conclusions Nightlife users’ perceptions of typical drunkenness in nightlife settings may be elevated and many of the heaviest drinkers are likely to drink beyond their ideal level of drunkenness. Findings can support emerging work to address cultures of intoxication in nightlife environments and suggest that interventions to correct misperceptions of normal levels of nightlife drunkenness may be of benefit

Aquatic laser fluorescence analyzer: field evaluation in the northern Gulf of Mexico

The new Aquatic Laser Fluorescence Analyzer (ALFA) provides spectral and temporal measurements of laser-stimulated emission (LSE) for assessment of phytoplankton pigments, community structure, photochemical efficiency (PY), and chromophoric dissolved organic matter (CDOM). The instrument was deployed in the Northern Gulf of Mexico to evaluate the ALFA analytical capabilities across the estuarine-marine gradient. The robust relationships between the pigment fluorescence and independent pigment measurements were used to validate the ALFA analytical algorithms and calibrate the instrument. The maximal PY magnitudes, PYm = PY(1-1.35·10−4PAR)−1, were estimated using the underway measurements of PY and photosynthetically active radiation (PAR). The chlorophyll (Chl) spatial patterns were calculated using the ratio of Chl fluorescence to PY to eliminate the effect of non-photochemical quenching on the underway Chl assessments. These measurements have provided rich information about spatial distributions of Chl, PYm, CDOM, and phytoplankton community structure, and demonstrated the utility of the ALFA instrument for oceanographic studies and bio-environmental surveys. The data suggest that the fluorescence measurements with 514 nm excitation can provide informative data for characterization of the CDOM-rich fresh, estuarine, and coastal aquatic environments

The Rare Decays \piee, \etaee and \etamumu$ in Chiral Perturbation Theory

We calculate the decay rates for \piee, \etaee and \etamumu in chiral perturbation theory. The linear combination of counterterms necessary to render these amplitudes finite is fixed by the recently measured branching fraction for \etamumu. We find \Br(\piee ) = 7\pm 1\times 10^{-8} and \Br(\etaee )=5\pm 1\times 10^{-9}.Comment: (6 pages, 1 figure available on request, uses harvmac.tex), UCSD/PTH 92-23, CALT-68-180

Long View (41RB112): Data Recovery of Two Plains Village Period Components in Roberts County, Texas, Volume 1

This archeological data recovery investigation in Roberts County in the northeastern panhandle of Texas was necessitated by the proposed widening of State Highway 70 (CSJ: 0490-04-037) by the Texas Department of Transportation (TxDOT), Amarillo District. This proposed highway rehabilitation program will directly impact a roughly 10 meter (m, 30 ft.) wide north-south section of prehistoric site 41RB112, the Long View site. This site consists of two horizontally distinct Plains Village period occupations shallowly buried along a linear interfluvial ridge between two small tributary creeks to the Canadian River in the midslope of this broad, dissected valley. This site was initially discovered by TxDOT archeologist, Dennis Price in June 2004 during an archeological inventory of the proposed 9.7 kilometer (6 mile) section north of the Canadian River in response to the planned highway rehabilitation program. Based on Mr. Price’s discovery of multiple artifact classes in buried context he recommended this site be assessed for its eligibility for listing on the National Register of Historic Places under criterion d and possible designation as a State Archeological Landmark (SAL) per the requirements of Section 106 of the National Historic Preservation Act (NHPA) and other related legislation. Following the Texas Historical Commissions concurrence with that recommendation, TxDOT through the Environmental (ENV) Affairs Division, contracted to TRC Environmental Corporation (TRC) under an existing Scientific Services Contract No. 57XXSA006 and issued a Work Authorization to TRC of Austin to conduct the site eligibility assessment. During a site visit by TxDOT geoarcheologist James Abbott and TRC archeologist Mike Quigg in February 2005, the site boundaries were expanded to nearly 300 meters (m) along the proposed area of potential effect (APE). Investigative strategies were devised to assess the Long View site. In May 2005, TRC’s archeologists from Austin conducted archeological testing for a NRHP and SAL eligibility assessment investigation at 41RB112. The assessment along the 10-m-wide by 300-m-long APE was accomplished by hand-excavating 28 1-by-1 m units (totaling 16.8 m3), hand-excavating four narrow ca. 30 centimeter (cm) wide trenches (two in each area totaling nearly 32 linear meters), as well as cleaning and inspecting 28 m of existing road cut exposures. These investigations determined that cultural materials clustered at the northern and southern ends (Areas A and C respectively) of the site with nearly 120 m of noncultural bearing deposits (Area B) between the two concentrations. A 4-m-wide mechanically bladed fireguard paralleled the existing fenceline throughout the length of the APE and disturbed much of the near surface materials in that zone. The opposite, eastern side of the highway was investigated through the excavation of six 50-by-50 cm shovel tests, surface, and road cut inspection. Based on the results from the hand-excavations and various collections conducted during the site assessment, it became apparent that the two ends (Areas A and C) of the Long View site in TxDOT’s proposed APE contained well-defined cultural components in the top 50 cmbs. Each end appeared to represent habitation remains from single occupation episodes with potential structures, restricted to a narrow time period of less than 100 years between uncalibrated 630 and 710 B.P. of the Plains Village period. Rodent and natural disturbances had vertically displaced some small cultural objects within the sandy deposits, but the restricted period of occupation to roughly a 100 year period reduces this impact. TRC recommended the site was eligible for listing on the National Register and as a State Landmark. The Texas Historical Commissions concurred with that recommendation, and subsequently the ENV Affairs Division of TxDOT, again contracted to TRC under an existing Scientific Services Contract No. 575XXSA008 and issued a Work Authorization to TRC Austin to perform the mitigation of the proposed impacts. Data recovery investigations were conducted during August through November 2006 along the western side of the existing highway. The previously identified northern-Area A and southern–Area C areas with high concentrations of cultural materials were targeted. These investigations began with a thorough geophysical survey that employed three noninvasive electrical detective instruments across Areas A and C anticipating to detect the locations of subsurface cultural features to target by hand-excavations. Some excavations targeted the detected anomalies, whereas others targeted previously identified features. In the end, hand-excavated blocks were completed in Areas A and C. The excavations totaled 128 m2 in Area A and 93 m2 in Area C for a grand total of 221 m2 or 103.4 m3. In conjunction with the archeological excavations, geoarcheological investigations focused on defining the age and development of the natural Holocene sediments that contained the cultural materials. The geoarcheological assessment included detailed stratigraphic documentation of site and near site deposits, sediment texture characterization, soil thin sections, magnetic susceptibility, multiple chemical analyses (organic, calcium, and phosphorus). Detailed stratigraphic data was also collected at two rare pithouse structures to pursue construction and filling episodes. The excavations yielded significant and diverse cultural assemblages from the two occupations assigned Component A and C. Both components are attributed to the Plains Village period with two discrete occupations dating to uncalibrated 460 to 535 B.P. (cal A.D. 1398 to 1447) in Component A and 530 to 700 B.P. (cal A.D. 1280 to 1437) in Component C. The two assemblages are significant not only in their diversity and quality of materials but also in the information they yielded. This report represents one of the first complete documents to present the entire cultural assemblage from a single site for this time period and region. The total recovered assemblage includes 157 formal chipped and ground stone tools, 226 informal tools, 3,414 pieces of lithic debitage, over 6,400 faunal fragments (1.4 kg), some 1,541 ceramic sherds, 1,790 burned rocks, at least 116 macrobotanical samples that includes 16 maize cobs, two human burials, and remains of a third, juvenile scattered along a previously bladed fireguard, 32 intact cultural features that include two rare pithouses, and other cultural debris related to these two campsites. The human remains and associated artifacts will be repatriated in accord with the requirements of the Native American Graves Protection and Repatriation Act (NAGPRA). A suite of 10 technical analyses directed at mostly the cultural assemblages included; use-wear, phytolith, diatom, petrography, macrobotanical, starch grain, instrumental neutron activation, bison bone isotopes, obsidian sourcing, radiocarbon and optical stimulated dating. This data was used to address 11 specific research questions concerning these Plains Village period occupations. Not only does the cultural debris contribute to our understanding of the time period but the geoarcheological information obtained explains the conditions and how the materials were preserved, and inform us concerning the past depositional environment in this immediate area. The combined information contributes to a significant understanding to a specific part of the Plains Village cultures in the Texas panhandle. Following the acceptance of the final report by the TxDOT and the Texas Historical Commission these cultural materials and all the documentation from the combined investigations will be permanently curated at Texas State University in San Marcos, Texas. The curated materials will provide important data that can be researched by interested parties in the future

Violence-related ambulance call-outs in the North West of England: a cross-sectional analysis of nature, extent and relationships to temporal, celebratory and sporting events.

OBJECTIVE: The aim of this study was to explore the potential of ambulance call-out data in understanding violence to inform about prevention activity. METHOD: This cross-sectional (2013-2015) study examined the nature, extent and characteristics of violence-related ambulance call-outs (n=15 687) across North West England and relationships with temporal, celebratory and sporting events. RESULTS: The majority of call-outs were for men, with a mean age of 33 years. Most call-outs were to deprived (64.4%) and urban (65.4%) areas and occurred at night (18:00-5:59; 75.2%). Three-quarters (77.3%) were recorded as assault/sexual assault and 22.7% stab/gunshot/penetrating trauma. Significant differences in call-out characteristics were identified between the two violence types. Generalised linear modelling found that call-outs significantly increased on weekends, New Year's Eve and weekday bank holiday eves (except for stab/gunshot/penetrating trauma). No significant associations between all violence call-outs, the two violence categories and sporting or celebration events were identified. Two-thirds (66.1%) of the call-outs were transferred to another health service for further assessment and/or treatment. The odds of being transferred were significantly higher among men (adjusted OR (AOR) 1.5, 95%CI 1.4 to 1.6), those aged 13-24 years (AOR 1.2, 95%CI 1.0 to 1.4), call-outs for stab/gunshot/penetrating trauma (AOR 1.4, 95%CI 1.3 to 1.5) and call-outs on Fridays/Saturdays (AOR 1.1, 95%CI 1.0 to 1.2) and lower for call-outs on New Year's Eve (AOR 0.6, 95%CI 0.4 to 0.9). CONCLUSION: Ambulance call-out data can provide a wealth of information to understand violence and subsequently inform about violence prevention and response activity. Ambulance services and staff could play a key role in preventing violence through sharing data and identifying and supporting victims

The impact of adverse childhood experiences on health service use across the life course using a retrospective cohort study

Objectives: The lifelong health impacts of adverse childhood experiences are increasingly being identified, including earlier and more frequent development of non-communicable disease. Our aim was to examine whether adverse childhood experiences are related to increased use of primary, emergency and in-patient care and at what ages such impact is apparent. Methods: Household surveys were undertaken in 2015 with 7414 adults resident in Wales and England using random probability stratified sampling (age range 18–69 years). Nine adverse childhood experiences (covering childhood abuse and household stressors) and three types of health care use in the last 12 months were assessed: number of general practice (GP) visits, emergency department (ED) attendances and nights spent in hospital. Results: Levels of use increased with increasing numbers of adverse childhood experiences experienced. Compared to those with no adverse childhood experiences, odds ( 95% CIs) of frequent GP use ( 6 visits), any ED attendance or any overnight hospital stay were 2.34 (1.88–2.92), 2.32 (1.90–2.83) and 2.67 (2.06–3.47) in those with 4 adverse childhood experiences. Differences were independent of socio-economic measures of deprivation and other demographics. Higher health care use in those with 4 adverse childhood experiences (compared with no adverse childhood experiences) was evident at 18–29 years of age and continued through to 50–59 years. Demographically adjusted means for ED attendance rose from 12.2% of 18-29 year olds with no adverse childhood experiences to 28.8% of those with 4 adverse childhood experiences. At 60–69 years, only overnight hospital stay was significant (9.8% vs. 25.0%). Conclusions: Along with the acute impacts of adverse childhood experiences on child health, a life course perspective provides a compelling case for investing in safe and nurturing childhoods. Disproportionate health expenditure in later life might be reduced through childhood interventions to prevent adverse childhood experiences

Decay-accelerating factor expression in the rat kidney is restricted to the apical surface of podocytes

Decay-accelerating factor expression in the rat kidney is restricted to the apical surface of podocytes.BackgroundDecay-accelerating factor (DAF) has inhibitory activity toward complement C3 and C5 convertases. DAF is present in human glomeruli and on cultured human glomerular visceral epithelial cells (GEC). We studied the distribution and function of rat DAF.MethodsFunction-neutralizing antibodies (Abs) were raised against DAF. The distribution of DAF in vivo was determined by immunoelectron microscopy. Functional studies were performed in cultured GEC and following IV injection of anti-DAF Abs into rats.ResultsDAF was present exclusively on the apical surfaces of GEC, and was not present on the basal surfaces of GEC, nor other glomerular or kidney cells. DAF was functionally active on cultured GEC, and served to limit complement activation in concert with CD59, an inhibitor of C5b-9 formation. Upon injection into normal rats, anti-DAF F(ab′)2 Abs bound to GEC in vivo, yet there was no evidence for complement activation and animals did not develop abnormal albuminuria. Anti-megalin complement-activating IgG Abs were “planted” on GEC, which activated complement as evidenced by the presence of C3d on GEC. Attempts to inhibit DAF function with anti-DAF Abs did not affect the quantity of complement activation by these anti-megalin Abs, nor did it lead to development of abnormal albuminuria. In contrast, in the puromycin aminonucleoside model of GEC injury and proteinuria, anti-DAF Abs slowed the recovery from renal failure that occurs in this model.ConclusionIn cultured rat GEC, DAF is an effective complement regulator. In vivo, DAF is present on GEC apical surfaces. Yet, it appears that DAF is not essential to prevent complement activation from occurring under normal circumstances and in those cases in which complement-activating Abs are present on the basal surfaces of GEC in vivo. However, in proteinuric conditions, DAF appears to be protective to GEC

Drunk and Disorganised: Relationships between Bar Characteristics and Customer Intoxication in European Drinking Environments

Preventing alcohol-related harm in drinking environments is a growing international priority. Factors relating to the physical, social and staffing environments in bars can contribute to increased alcohol consumption and harm. Understanding the relationships between such factors and intoxication in European drinking environments is critical to developing appropriate interventions. We undertook a quantitative observational study in 60 bars in four European cities, in The Netherlands, Slovenia, Spain and the UK (n = 237 observational visits). Using a structured observational schedule, researchers recorded characteristics of the bar environment and rated customer intoxication levels. All physical bar characteristics showed associations with intoxication before interactions between them were controlled for. Hierarchical modelling found significant independent associations between intoxication and use of plastic glassware, promotion of non-alcoholic drinks (often energy drinks), permissive environments, poor washroom facilities, the presence of a dance floor, customer sexual activity/competitiveness and later observational time. Findings suggest that prevention efforts should focus on raising and enforcing managerial standards in bars. While harm reduction measures such as plastic glassware are often promoted for high risk bars, such measures are inadequate to address public health concerns and insufficient to demonstrate social responsibility

STOP-sexual violence: evaluation of a community-based nightlife worker awareness raising bystander training programme

Background: Preventing sexual violence in nightlife environments is a pervasive issue across many countries. This study explored the associated impact of a nightlife worker sexual violence awareness raising/bystander training programme (STOP-SV) on trainees’ sexual violence myth acceptance and readiness and confidence to intervene. Methods: Pre- and post-test (n = 118), and 3-month follow-up (n = 38) trainee surveys were implemented across three countries (Czech Republic, Portugal and Spain). Paired-sample tests examined changes across time-periods in participants’ myth acceptance (e.g. unwanted sexual advances are a normal part of a night out), and readiness and confidence to intervene. Multi-nominal regression was used to examine the relationship between the change in pre-to-post-training scores and trainee characteristics. Results: Compared to pre-training, post-training participants were significantly (P < 0.01) less likely to agree with sexual violence myths, and more likely to be ready and confident to intervene. In bi-variate and multi-variate analyses, we found no significant associations between the change in pre-to-post-training scores and trainee characteristics. Analyses of the small follow-up sub-sample illustrated some positive changes at the post-training and follow-up time-periods (i.e. reduction in sexual violence myth acceptance). Conclusion: This exploratory study suggests that the STOP-SV training programme was associated with a decrease in trainees’ acceptance of sexual violence myths, and an increase in their readiness and confidence to intervene. Our findings support the case for further implementation and evaluation of awareness raising/bystander programmes for nightlife workers that aim to prevent and respond to sexual violence